ICU Decoded › Library › Ward Pathways › Emergency / Toxicology › Snakebite Envenomation
Snakebite EnvenomationICU / resuscitation
Emergency / Toxicology · Ward Pathways · Locked — free with a referral
By Dr Javed Akhtar · Last reviewed 2 October 2026
Presentation Farmer bitten on the foot while harvesting at night 3 h ago; swelling to the knee, bleeding gums; 20-minute whole-blood clotting test (20WBCT) — blood not clotted (viper); or painless bite, ptosis and difficulty swallowing (krait/cobra)
Red flags 20WBCT not clotted / spontaneous bleeding Ptosis, bulbar weakness, falling SpO₂ Oliguria, dark urine Hypotension Swelling crossing a joint within hours
Differential diagnosis Dry bite / anxiety Scorpion sting (autonomic storm, pulmonary oedema) Other bites (rodent, insect) Guillain–Barré or myasthenia (painless krait neurotoxicity) Other causes of coagulopathy
When to admit, call ICU or discharge Admit: Every snakebite for ≥24 h observationICU: Neurotoxic paralysis, shock, AKI needing dialysis, severe bleedingIntubate: Bulbar failure, respiratory weakness, falling SpO₂Dialysis: AKI with AEIOU indications (often Russell's viper)
Key points India has the world's highest snakebite mortality — the "Big Four": Russell's viper, saw-scaled viper (haemotoxic), common krait, cobra (neurotoxic). 20WBCT is the bedside test that drives ASV — use a new, clean, dry glass tube. Early ventilation keeps krait victims alive until the neurotoxicity wears off (days).
Never Apply a tourniquet, incise, suck or apply herbs to the bite Give ASV to an asymptomatic bite with normal 20WBCT (dry bite) Give routine premedication or a test dose of ASV Discharge a painless night-time bite before 24 h (krait) Give IM injections or NSAIDs to a coagulopathic patient
Common mistakes Tourniquets and cuts Premedication/test dose delaying ASV Early discharge of krait bites Waiting for ASV to reverse paralysis instead of ventilating
Disposition and follow-up Ward/ICU with ventilator and dialysis access; transfer early if unavailable. Follow-up for AKI recovery and hypopituitarism.
Locked ABCDE first moves The step-by-step decision sequence Order set Monitoring timeline and escalation triggers Treatment doses and preparation Discharge package Open the full pathway in Ward Pathways
Free with a referral from any ICU Decoded member, or by applying with your medical registration. How access works .
← Organophosphate Poisoning · Digoxin Toxicity →
More Emergency / Toxicology pathways
Part of Emergency / Toxicology in Ward Pathways — open the interactive version .