Diabetic 60-year-old, 3 days of fever, cough with rusty sputum, right pleuritic pain; RR 28, BP 100/60, urea 50 mg/dL, confused — CURB-65 = 4; right lower lobe consolidation
Red flags
Septic shock
RR ≥30 or SpO₂ <90%
Confusion
Multilobar consolidation
Empyema
Differential diagnosis
Heart failure
Pulmonary embolism with infarct
TB
Melioidosis, scrub typhus, leptospirosis
Lung cancer with post-obstructive pneumonia
When to admit, call ICU or discharge
Admit: CURB-65 ≥2, hypoxia, unable to take oral, comorbidity
ICU: Septic shock, invasive ventilation, or ≥3 minor criteria (RR ≥30, PaO₂/FiO₂ ≤250, multilobar, confusion, urea ≥20 mg/dL, WBC <4000, platelets <100k, T <36 °C, hypotension needing aggressive fluids)
Intubate: Refractory hypoxaemia, exhaustion, ↓GCS
Vasopressors: Septic shock after fluids — noradrenaline
Key points
Commonest bacterial cause is still Streptococcus pneumoniae; atypicals (Mycoplasma, Legionella) are covered by the macrolide.
Non-resolving pneumonia at 6 weeks, especially in smokers >50, needs repeat CXR ± CT (cancer, TB).
Vaccination: pneumococcal and influenza for all adults ≥50 y and at-risk groups.
Never
Delay antibiotics for cultures in septic CAP
Use fluoroquinolone monotherapy as first choice where TB is common without sending sputum for TB
Give broad MRSA/Pseudomonas cover without risk factors
Give steroids in influenza pneumonia
Common mistakes
Wrong severity triage
FQ masking TB
Missing tropical mimics
No follow-up CXR in smokers
Disposition and follow-up
CURB-65-guided site of care; ICU for severe criteria; review at 48–72 h and CXR at 6 weeks if risk factors.
ICU Decoded — original critical-care and internal-medicine pathways by
Dr Javed Akhtar, each cited to a current guideline. For education and quick
reference; verify every dose against local protocols before prescribing.