ICU Decoded › Library › Ward Pathways › Gastroenterology › Gastrointestinal Bleeding
Gastrointestinal BleedingICU / resuscitation
Gastroenterology · Ward Pathways · Locked — free with a referral
By Dr Javed Akhtar · Last reviewed 2 October 2026
Presentation Two episodes of haematemesis and melaena since morning; HR 118, BP 92/60; on aspirin and ibuprofen (or known cirrhosis)
Red flags Shock index >1 Haematemesis with instability Rebleeding Encephalopathy in cirrhosis
Differential diagnosis Peptic ulcer Oesophageal/gastric varices Mallory–Weiss tear Erosive oesophagitis/gastritis Malignancy Aorto-enteric fistula (previous AAA graft)
When to admit, call ICU or discharge Admit: All except Glasgow-Blatchford 0–1ICU: Shock, ongoing bleeding, variceal bleed, rebleed, need for airway protectionIntubate: Massive haematemesis, GCS low, before endoscopy in active variceal bleeding with encephalopathyTransfuse: Hb <70 g/L (restrictive), <80 g/L with cardiovascular disease; massive haemorrhage protocol if unstableVasopressors: Only as a bridge — haemostasis and blood come first
Key points Variceal bleeding: vasoactive drug + antibiotic + band ligation within 12 h — the triad that saves lives. Continuing aspirin for secondary prevention after ulcer bleeding reduces mortality, even though rebleeding rises slightly. Lower GI bleed with shock: CT angiography first; most stop spontaneously; colonoscopy after bowel prep in stable patients.
Never Give tranexamic acid for GI bleeding (HALT-IT: no benefit, more VTE and seizures) Over-transfuse a variceal bleed (raises portal pressure) Forget antibiotics in a cirrhotic GI bleed Leave NSAIDs on the discharge chart
Common mistakes Under-resuscitation or over-transfusion Missing varices (no terlipressin or antibiotics) Delaying endoscopy >24 h Tranexamic acid
Disposition and follow-up Endoscopy within 24 h; ICU for instability or variceal bleeding; follow-up scope for gastric ulcers at 6–8 weeks.
Locked ABCDE first moves The step-by-step decision sequence Order set Monitoring timeline and escalation triggers Treatment doses and preparation Discharge package Open the full pathway in Ward Pathways
Free with a referral from any ICU Decoded member, or by applying with your medical registration. How access works .
← Head Trauma — Subdural Hematoma · Inflammatory Bowel Disease →
More Gastroenterology pathways
Part of Gastroenterology in Ward Pathways — open the interactive version .