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Upper GI bleedRefer
Gut & liver · OPD · Locked · first month free
By Dr Javed Akhtar · Last reviewed 2 October 2026
Drugs on this card
Variceal: Terlipressin, Octreotide (alternative), Ceftriaxone
Non-variceal: Pantoprazole, Packed red cells
Advice and when to refer Endoscopy: Within 12 h for varices (band ligation); within 24 h for other bleeds (Baveno VII 2022; ACG 2021)Not used: Tranexamic acid (no benefit, more clots); Glasgow-Blatchford score 0–1 can go home (HALT-IT 2020; ACG 2021)
Investigations
Resuscitate first; endoscopy within 12 h for varices and 24 h for other bleeds.
First visit CBC, blood group and crossmatch — Every patient.PT/INR, LFT, urea, creatinine — Liver disease and blood urea rise.Upper GI endoscopy — Diagnosis and treatment.
Only if indicated HBsAg and anti-HCV — Suspected cirrhosis.USG abdomen with portal Doppler — Suspected portal hypertension.ECG and troponin — Elderly or heart disease with major blood loss.
Follow-up and monitoring Haemoglobin — Every 6–12 h while bleeding; transfuse to 7–8 g/dL.
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