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Fever & infections · OPD · Locked · first month free
By Dr Javed Akhtar · Last reviewed 2 October 2026
Drugs on this card
Benzathine penicillin (primary, secondary, early latent < 1 y), Benzathine penicillin (late latent or unknown duration), Doxycycline (penicillin allergy, not pregnant)
Advice and when to refer Pregnancy: Penicillin only — desensitise if allergic; treat the partner; baby reviewed at birth (NACO 2024; CDC 2021)Investigations
First visit RPR or VDRL with titre — Non-treponemal test; titre is used to follow treatment.TPHA or treponemal rapid test — Confirms a reactive RPR/VDRL.HIV test — Every patient with syphilis.Only if indicated CSF VDRL — Neurological, eye or ear symptoms — at a higher centre.Antenatal syphilis test — Every pregnant woman at the first visit.Follow-up and monitoring RPR/VDRL titre at 6 and 12 months — A fourfold fall shows response.
Locked The adult dose for each drug Indian brand names for each drug, with a link to buy Open Syphilis in OPD
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