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Sjögren syndromeRefer
Bones & joints · OPD · Locked · first month free
By Dr Javed Akhtar · Last reviewed 2 October 2026
Drugs on this card
Carboxymethylcellulose 0.5% (dry eyes), Pilocarpine (dry mouth with some gland function left), Hydroxychloroquine (joint pain or arthritis)
Advice and when to refer Mouth care: Sugar-free gum, frequent sips of water, fluoride toothpaste, dental review every 6 months (EULAR 2019, latest)Refer urgently: Persistent parotid swelling, lymph nodes, purpura or low C4 (lymphoma risk) (EULAR 2019, latest)
Investigations
First visit Anti-Ro (SSA) and anti-La (SSB), ANA — Supports the diagnosis.Schirmer test — Dry eyes.CBC, ESR, RA factor — Baseline.
Only if indicated Lip (minor salivary gland) biopsy — Antibody negative but strong suspicion.Serum protein electrophoresis, complement — Lymphoma risk (persistent gland swelling).Eye examination — Before hydroxychloroquine.
Locked The adult dose for each drug Indian brand names for each drug, with a link to buy Open Sjögren syndrome in OPD
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