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Leptospirosis
Fever & infections · OPD · Locked · first month free
By Dr Javed Akhtar · Last reviewed 2 October 2026
Drugs on this card
Doxycycline, Amoxicillin (pregnancy, breastfeeding, under 8 y)
Severe: Crystalline penicillin, Ceftriaxone (penicillin allergy)
Prophylaxis (during exposure): Doxycycline
Investigations
First visit Leptospira IgM ELISA — From day 5 of fever; a rapid card test may be used where ELISA is not available.CBC, creatinine, LFT — Kidney and liver involvement decide referral.Urine routine — Protein, blood and casts.
Only if indicated Microscopic agglutination test (MAT) — Confirmation at a reference laboratory.Chest X-ray, CK — Breathlessness, haemoptysis (pulmonary haemorrhage) or severe muscle pain.Malaria, dengue, scrub typhus tests — Same season and overlapping features.
Locked The adult dose for each drug The child dose, where the card gives one Indian brand names for each drug, with a link to buy Open Leptospirosis in OPD
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