Thunderclap headache: urgent noncontrast CT. If negative and presentation is >6 h or there is a new deficit, do an LP when safe. Within 6 h, a high-quality CT read by an expert can exclude SAH in a neurologically intact patient. CTA or DSA finds the aneurysm.
Secure a ruptured aneurysm as early as you can, preferably within 24 h, by coiling or clipping. Until then, avoid severe hypertension, hypotension and BP swings with short-acting drugs; SBP <160 is a local target, not a universal 2023 guideline one.
Give nimodipine 60 mg q4h ×21 d to every patient; delayed cerebral ischemia peaks on day 4–14, so track TCDs and exams.
Initial Workup and Management of Subarachnoid Hemorrhage
Sudden severe headache ± loss of consciousness: suspect SAH and get a noncontrast CT now. If CT is negative, do an LP (when safe) if presentation is >6 h or there is a new deficit. Within 6 h, a high-quality CT read by an expert may be enough in a neurologically intact patient.
Admit to a neuro-ICU: protect the airway; monitor neuro status, BP and ECG closely; control pain; avoid severe hypertension, hypotension and BP swings. No routine antifibrinolytics. Get vascular imaging. Symptomatic hydrocephalus needs urgent CSF diversion. Treat seizures; reserve prophylaxis for selected high-risk patients. Start enteral nimodipine early.
Aneurysm or other vascular malformation identified?
Yes
Secure aneurysm/vascular malformation to prevent rebleeding: neurosurgery plus neurointerventionalist consults to pick optimal plan (clipping vs. coiling of aneurysms, embolization vs. resection of AVM) · aneurysm treatment within 24 hours strongly recommended · evacuate hematoma if focal deficits with herniation or increased ICP
Aneurysm secured (successfully clipped or coiled)
Continue enteral nimodipine 60 mg every 4 h (usually 21 days) and keep euvolaemic. Do not raise BP to prevent vasospasm; consider BP augmentation only for symptomatic delayed cerebral ischaemia after assessment.
Watch for common complications: frequent neurologic examination · ICP monitoring if appropriate · frequent checks of vitals, heart rhythm, electrolytes · Foley catheter for close input/output tracking · → Pathway 26.2
No
Digital subtraction angiography if CTA or MRA used initially · consider other cause (trauma, PMSAH) · repeat angiography in 1–3 weeks
Managing Complications After Subarachnoid Hemorrhage
Altered mental status or new neurologic deficit after SAH
Timing since initial event?
Yes
4–21 days after the initial event — vasospasm suspected? Fluctuating mental status · new focal neurologic deficit · Fisher grade ≥3 on initial head CT · increased flow velocities on TCD
Vasospasm strongly suspected?
Yes
Suspected symptomatic DCI: first exclude rebleeding, hydrocephalus, seizures and metabolic causes; keep euvolaemic. Once the aneurysm is secured, a trial of raised BP may be reasonable, judged by neurological response and cardiac tolerance. Persistent deterioration needs urgent neurovascular review. There is no fixed MAP percentage or set waiting time.
Endovascular therapy for angiographic vasospasm: intra-arterial verapamil, nimodipine, nicardipine, or milrinone · balloon angioplasty (proximal intracranial vessel segments)
ICU Decoded — original critical-care and internal-medicine pathways by
Dr Javed Akhtar, each cited to a current guideline. For education and quick
reference; verify every dose against local protocols before prescribing.