Built from the KDIGO 2012 Clinical Practice Guideline for Acute Kidney Injury (effluent dose, citrate-first anticoagulation), the Ronco (2000)/ATN (2008)/RENAL (2009) trials, and regional citrate anticoagulation (RCA) literature (verified July 2026), alongside the uploaded CRRT masterclass reference material. This tool assists calculation and organization only — always follow your institution's CRRT protocol, nephrology/critical care guidance, and your device manufacturer's instructions. CRRT circuit setup, anticoagulation, and dosing decisions carry real patient-safety stakes; verify every value here before acting on it.